4-Amino-1-[4-amino-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one - Names and Identifiers
Name | 3'-amino-2',3'-dideoxycytidine
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Synonyms | 3'-NH2-ddC 3'-amino-2',3'-dideoxycytidine 4-Amino-1-[4-amino-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one 4-amino-1-(3-amino-2,3-dideoxypentofuranosyl)pyrimidin-2(1H)-one 2(1H)-pyrimidinone, 4-amino-1-(3-amino-2,3-dideoxypentofuranosyl)- 4-Amino-1-((2R,4S,5S)-4-amino-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
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CAS | 84472-90-2
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InChI | InChI=1/C9H14N4O3/c10-5-3-8(16-6(5)4-14)13-2-1-7(11)12-9(13)15/h1-2,5-6,8,14H,3-4,10H2,(H2,11,12,15) |
4-Amino-1-[4-amino-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one - Physico-chemical Properties
Molecular Formula | C9H14N4O3
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Molar Mass | 226.23 |
Density | 1.73g/cm3 |
Melting Point | >210°C (dec.) |
Boling Point | 450.2°C at 760 mmHg |
Flash Point | 226°C |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Vapor Presure | 5.38E-10mmHg at 25°C |
Appearance | Solid |
Color | White to Off-White |
Storage Condition | Hygroscopic, -20°C Freezer, Under inert atmosphere |
Stability | Hygroscopic |
Refractive Index | 1.743 |
4-Amino-1-[4-amino-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one - Introduction
3 '-amino-2',3 '-dideoxycytidine is a compound whose chemical formula is C9H13N3O3. Here are some properties and information about this compound:
1. nature:
-Appearance: a solid
-Solubility: Soluble in water and some organic solvents
-Melting point: approximately 218-220°C
2. use:
-Biomedical research: 3 '-amino-2',3 '-dideoxycytidine can be used for the synthesis of RNA chain extension inhibitors, used to study RNase activity and RNA modification and RNA-related biological processes.
-Chemical synthesis: It can also be used as an important intermediate in organic synthesis.
3. preparation method:
-Under normal circumstances, the synthesis of 3 '-amino-2',3 '-dideoxycytidine is achieved through chemical synthesis, which requires the use of corresponding chemical reagents and reaction conditions.
4. Safety Information:
-Safety measures such as wearing appropriate personal protective equipment (e. g. gloves, goggles, etc.) are required when using or handling this compound.
-Amino compounds may be irritating and allergic, so be careful when handling.
-Toxicity information is limited, so more experimental evidence and research data are necessary.
Last Update:2024-04-10 22:29:15